Aprepitant

[SDL] Aprepitant Capsule 80 mg & 125 mg (Tripack)

[MAF] Aprepitant Capsule 80 mg

1. Prevention of chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy

Legend

This section shows the following:

• Subsidy Scheme and Clinical Indication (where applicable) of drugs listed in the MOH List of Subsidised Drugs

• Subsidised brands of vaccines recommended in the National Immunisation Schedules listed in the MOH Subsidised Vaccine List

• Cancer Drug and Clinical Indication listed in the MediShield Life Cancer Drug List

As this website is updated monthly, please refer to MOH List of Subsidised Drugs, MOH Subsidised Vaccine List or MediShield Life Cancer Drug List for the most updated information.

31/08/2022 Review of cancer supportive care medicines

The Ministry of Health’s Drug Advisory Committee has reviewed the available clinical evidence for cancer supportive care medicines routinely used in public healthcare institutions to update the MOH List of Subsidised Drugs in line with local clinical practice. The following medicines have been recommended for inclusion on the MOH Standard Drug List (SDL) or Medication Assistance Fund (MAF) in line with their registered indications or specific clinical criteria for cancer supportive care, in view of clinical need and acceptable clinical and cost-effectiveness:

• Aprepitant 125 mg and 80 mg tri-pack capsules;

• Cetirizine 10 mg tablet;

• Denosumab 60 mg/mL prefilled syringe;

• Denosumab 120 mg/1.7 mL solution for injection;

• Epoetin alfa 10,000 international units/mL and 40,000 international units/mL prefilled syringes;

• Epoetin beta 10,000 international units/0.6 mL and 30,000 international units/0.6 mL prefilled syringes;

• Folic acid 400 mcg tablet;

• Granisetron 1 mg tablet;

• Granisetron 1 mg/mL and 3 mg/3 mL solution for injection;

• Ketamine 500 mg/10 mL solution for injection;

• Montelukast 10 mg tablet;

• Oxycodone 5 mg and 10 mg capsules;

• Posaconazole 100 mg delayed-release tablet;

• Pegfilgrastim biosimilar (Fulphila) 6 mg/0.6 mL prefilled syringe;

• Pregabalin 25 mg, 50 mg, 75 mg, 100 mg, 150 mg and 300 mg capsules;

• Ranitidine 150 mg tablet; and

• Voriconazole 50 mg and 200 mg tablets.

[NR] Medicines that have not been recommended for subsidy due to unacceptable cost-effectiveness are listed in the Annex.

The clinical indications, subsidy class and subsidy implementation dates (if applicable) for all medicines included in the review are provided in the Annex.

Legend

This section displays recommendation from the MOH Drug Advisory Committee for subsidy and appropriate use of the drug as extracted from the Agency for Care Effectiveness (ACE) Drug Guidances. As this website is updated monthly, please refer to the ACE website for the most updated information.

Note:

General availability information reflected is based on the Public Healthcare Institutions’ (PHI) formulary on what is commonly used for treating their patient population and may or may not be available for patients not under the care of that institution. It does not reflect the PHI’s actual inventory availability and is subjected to change. Please consult the Public Hospitals or Polyclinics for details on availability and supply restrictions/considerations. General availability is not tied to any brand unless otherwise stated.

Users are to consult the respective PHIs for actual inventory availability and supply restrictions/consideration