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CHLOROQUINE TABLETS 250 MG [SIN01559P]

Active ingredients: CHLOROQUINE TABLETS 250 MG

Last updated 26 October 2025

Product Info

CHLOROQUINE TABLETS 250 MG

[SIN01559P]

Product information

Active Ingredient and Strength

CHLOROQUINE PHOSPHATE - 250 MG

Dosage Form

TABLET, FILM COATED

Manufacturer and Country

BEACONS PHARMACEUTICALS PTE. LTD. - SINGAPORE

Registration Number

SIN01559P

Licence Holder

BEACONS PHARMACEUTICALS PTE. LTD.

Forensic Classification

PHARMACY ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

P01BA01

THERAPEUTIC PROPERTIES:
Chloroquine is used for the suppression and treatment of malaria. It is especially active against the erythrocytic forms of malaria parasites. It is not active against tissue forms of the malaria parasites.

DOSAGE:
Suppression in adults: 500mg (300mg base) on the same day each week, beginning 2 weeks prior to exposure, continued for 4 – 8 weeks after leaving the area. If treatment begins on exposure, a loading dose of 1 gm can be taken in divided doses 6 hours apart.
Suppression in children: 5mg base/kg/week. The loading dose is 10mg base/kg/week.
Acute attacks in adults: an initial dose of 1 gm (600mg base), followed by 500mg (300mg base) after 6 to 8 hours and a single dose of 500mg (300mg base) on each of 2 consecutive days.

Table caption

For children: A total of 25mg / kg is given over 3 days.

First dose

: 10mg base/kg


Second dose

: 5mg base/kg, 6 hours after the first dose


Third dose

: 5mg base/kg, 18 hours after the second dose


Fourth Dose

: 5mg base/kg, 24 hours after the third dose

For a radical cure of vivax and malariae malaria, concomitant therapy with an 8-aminoquinoline compound like primaquine is necessary.

CONTRAINDICATIONS:
Chloroquine is contraindicated in the presence of retinal or visual field changes of any aetiology, in patients with psoriasis or porphyria, and in patients with known hypersensitivity to 4-aminoquinolines. However, the drug can be used in these cases in acute attacks of malaria if the physician elects to use it after carefully weighing the possible risks and benefits to the patient.