EROGRAN FOR ORAL SUSPENSION 200 MG/5 ML [SIN08042P]

Product Info

EROGRAN FOR ORAL SUSPENSION 200 MG/5 ML

[SIN08042P]

INDICATIONS
Indicated in the treatment or prophylaxis of the following:

• Upper and lower respiratory tract infections.

• Skin and soft-tissue infections including erythrasma.

• Genitourinary tract infections including gonorrhoea and syphilis.

• Intestinal amoebiasis.

• Others include bacterial endocarditis, streptococcal pharyngitis, diphtheria, Legionnaires' disease and pertussis.

DOSAGE AND ADMINISTRATION
Adults

• Antibacterial
  Oral, the equivalent of erythromycin 400 mg every 6 hours or 800 mg every 12 hours.

• Antibacterial (streptococcal prophylaxis)

  • Continuous prophylaxis of streptococcal infections in patients with a history of rheumatic heart disease and/or chorea.

  • Oral, the equivalent of erythromycin 400 mg every 12 hours.

• Antiprotozoal
  Oral, the equivalent of erythromycin 400 mg every 6 hours for ten to fourteen days.

• Gonorrhoea (disseminated)
  Oral, the equivalent of erythromycin 800 mg every 6 hours for seven days.

• Legionaires' Disease
  Oral, the equivalent of erythromycin 400 mg to 1 gram every 6 hours.

• Syphilis
  Oral, the equivalent of erythromycin 800 mg every 6 hours for 15 days (early syphilis) or for 30 days (late syphilis).

Usual adult prescribing limits
Antibacterial the equivalent of erythromycin up to 4 grams daily.

Note: Doses up to the equivalent of 8 grams of erythromycin daily are apparently well tolerated.

Children

• Antibacterial
  Oral, the equivalent of erythromycin 7.5 to 25 mg per kg of body weight every 6 hours or 15 to 50 mg per kg of body weight every 12 hours.

• Antiprotozoal
  Oral, the equivalent of erythromycin 7.5 to 12.5 mg per kg of body weight every 6 hours for 10 to 14 days.

Note: 1.17 grams of erythromycin ethylsuccinate are equivalent to approximately 1 gram of erythromycin.

To reconstitute, add cooled boiled water until well dispersed, then add water to the appropriate mark.

Note: The information given here is limited. For further information, consult your doctor or pharmacist.

CONTRAINDICATIONS

• Avoid in patients known to be hypersensitive to erythromycins

• Erythromycin is contraindicated in patients taking astemizole, terfenadine, domperidone, cisapride or pimozide

• Erythromycin should not be given to patients with a history of QT prolongation (congenital or documented acquired QT prolongation) or ventricular cardiac arrhythmia, including torsades de pointes (see "Warnings and Precautions" – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information)

• Erythromycin should not be given to patients with electrolyte disturbances (hypokalaemia, hypomagnesaemia due to the risk of prolongation of QT interval)