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VIRLESS TABLET 800 MG [SIN10084P]
Active ingredients: VIRLESS TABLET 800 MG
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Product Info
VIRLESS TABLET 800 MG
[SIN10084P]
Product information
Active Ingredient and Strength | ACYCLOVIR - 800 MG |
Dosage Form | TABLET |
Manufacturer and Country | Y S P INDUSTRIES (M) SDN BHD - MALAYSIA |
Registration Number | SIN10084P |
Licence Holder | YUNG SHIN PHARMACEUTICAL (SINGAPORE) PTE LTD |
Forensic Classification | PRESCRIPTION ONLY MEDICINES |
Anatomical Therapeutic Chemical (ATC) code | J05AB01 |
Indication(s):
Infections caused by Varicella-Zoster Virus.
Skin and mucous membrane infections due to Herpes Simplex Virus.
Prophylaxis of Herpes Simplex infection in patients who are immunocompromised including those with bone marrow transplant and leukemia.
Suppression of recurrent Herpes Simplex Virus infections.
Dosage and Administration:
I. Adult dose:
Treatment of Herpes Simplex Infection:
200mg (400mg in the immunocompromised patient) 5 times daily, usually for 5 days.
Prevention of recurrent Herpes Simplex Infection:
200mg to be taken 4 times daily, or 400mg twice daily, possibly reduced to 200mg 2 or 3 times daily.
Therapy should be interrupted periodically at interval 6 – 12 months in order to observe possible changes in the nature history of the disease.
Prophylaxis of Herpes Simplex Infection in immunocompromised patients:
200mg to be taken 4 times daily at approximately 6 hours interval. In situation of severe immunocompromised, eg., after bone marrow transplantation, or in patients with impaired gastrointestinal absorption, the dose may be doubled to 400mg.
Treatment of Varicella and Herpes Zoster infection:
800mg, 5 times daily for 7 days.
II. Pediatric Dose:
For treatment of Herpes Simplex Infection and for Prophylaxis of Herpes Simplex Infection in immunocompromised, children 2 years and over should be given adult dosage, and children < 2 years should be given half the adult dose.
For treatment of Varicella Infection,
children > 6 years : 800mg 4 times a day. 2 – 6 years : 400mg 4 times a day. below 2 years : 200mg 4 times a day. Dosing may be calculated as 20mg/kg body weight (not to exceed 800mg), 4 times daily.
Treatment should be continued for 5 days.
No specific data are available on the treatment of Herpes Simplex Infection in immune-competent children.
III. Dosage in Elderly
Elderly patients are more likely to have an age-related decrease in renal function, which may required an adjustment of dosage or dosing interval.
IV. Dosage in Renal Impairment
For patient with renal impairment (creatinine clearance < 10ml/min), the dosage should be decreased to 200mg every 12 hours for treatment of Herpes Simplex Infection, and 800mg twice daily for treatment of Varicella and Zoster Infection.
Contraindication(s):
Contraindicated in patients who develop hypersensitivity or intolerance to any of the components of the formulation.
