OFCIN FILM COATED TABLET 400 MG [SIN10118P]

Product Info

OFCIN FILM COATED TABLET 400 MG

[SIN10118P]

Indication(s):
For the treatment of infections caused by susceptible strains of microorganism in infections of the urinary tract, lower respiratory tract, skin and soft tissue, gonorrhoea and non-gonococcal urethritis and cervicitis.

Dosage and Administration:

1. Urinary tract infections: 200 to 400mg daily, preferably in the morning, increased if necessary in upper urinary tract infections to 400mg twice daily.

2. Lower respiratory tract infections: 400mg daily, preferably in the morning, increased if necessary to 400mg twice daily.

3. Skin and soft tissue infections: 200 to 400mg twice daily.

4. Uncomplicated gonorrhoea: 400mg as a single dose.

5. Non-gonococcal urethritis and cervicitis: 400mg daily in single or divided doses.

6. Renal impairment: When creatinine clearance is 20–50mL/minute, the dosage should be reduced by half (100–200mg). If creatinine clearance is less than 20mL/minute, 100mg should be given every 24 hours. In patients undergoing haemodialysis or peritoneal dialysis, 100mg should be given every 24 hours.

7. Liver impairment: Dose of ofloxacin should be reduced accordingly in patients with impaired liver function.

Contraindication(s):

1. Patient who has shown previous hypersensitivity to this drug or to other quinolone antibiotics.

2. Ofloxacin is contraindicated in patients with a history of epilepsy or with a lowered seizure threshold.

3. Ofloxacin is contraindicated in children or growing adolescents and in pregnant or breast-feeding women.